NEW YORK, NY (Oct 19, 2026)

Prime medical space in Manhattan doesn’t wait around. Turnkey suites ready for patient intake are being snapped up fast. For practices looking to expand, relocate, or lock in an iconic footprint right now, here are ten medical offices available for lease that require your immediate attention.

1. 1111 Park Avenue, Suite 1G

Upper East Side • New York City

Size: 2,250 SF | Rate: $22,000/month
Layout: 1 Office | 3 Exam Rooms | 2 Procedure Rooms
Why You Need to Move Fast: Turnkey surgical suites on Park Avenue are rare. Featuring its own dedicated private street entrance, this Carnegie Hill space lets surgical, cosmetic, and aesthetic practices bypass standard lobby traffic entirely.

Renovated suites with two procedure rooms are incredibly rare and do not stay vacant long.

2. 1727 Broadway, Suite 1

Midtown / Columbus Circle • New York City

Size: 5,700 SF | Rate: $37,500/month
Layout: 3 Offices | 13 Exam Rooms
Why You Need to Move Fast: Massive medical infrastructure ready to launch. With 13 exam rooms already configured, an urgent care operator, diagnostic center, physical therapy center, or multi-specialty network can bypass years of architectural planning.

3. Suite 3100 at Westfield WTC

Lower Manhattan • New York City

Size: 2,606 SF | Rate: Inquire for Pricing
Potential Layout: 5 Offices | 6 Exam Rooms
Why You Need to Move Fast: Direct, weather-proof access to 12 subway lines and the PATH hub puts this facility in front of tens of thousands of daily Financial District commuters.

Offering up to six exam rooms and five private consults, this space provides immediate visibility in Lower Manhattan's premier transit-integrated hub.

4. 815 Park Avenue, Suite 1AD

Upper East Side • New York City

Size: 2,000 SF | Rate: $20,000/month
Layout: 3 Offices | 3 Exam Rooms | 1 Procedure Room
Why You Need to Move Fast: Situated between East 74th and East 75th Streets, this suite positions your practice blocks from Lenox Hill Hospital and the city’s densest private-pay patient corridor.

With an existing procedure room and three exam rooms, it’s a turnkey setup for a specialist ready to sign and open.

5. 60 East 56th Street, 2nd Floor

Upper East Side • New York City

Size: 6,929 SF | Rate: $38,687/month
Layout: 4 Offices | 12 Exam Rooms | 1 Procedure Room
Why You Need to Move Fast: Nearly 7,000 square feet of full-floor medical real estate between Park and Madison Avenues is almost impossible to find. With 12 exam rooms already built out, multi-provider practices should tour immediately before it is leased to institutional healthcare operators.

6. 50 East 72nd Street, Suite 1B

Upper East Side • New York City

Size: 1,600 SF | Rate: $13,000/month
Layout: 2 Offices | 4 Exam Rooms | 1 Procedure Room
Why You Need to Move Fast: Medical suites with private outdoor space are virtually non-existent on the Upper East Side. At $13,000/month just off Park Avenue, this four-exam, single-procedure layout offers boutique luxury for private practitioners looking to move quickly.

7. Suite 3120 at Westfield WTC

Lower Manhattan • New York City

Size: 1,396 SF | Rate: Inquire for Pricing
Potential Layout: 3 Offices | 6 Dental Operatories
Why You Need to Move Fast: Up to six plumbed dental operatories in a high-traffic transit hub. This prime location offers unparalleled exposure with a built-in patient base of tens of thousands.

8. Park Sixty Medical at 110 E60th St

Plaza District • New York City

Size: Prebuilts & full floors from 2,083 SF to 13,253 SF
Layout: Flexible Prebuilts (e.g., Suite 1004 with 3 Offices, 6 Exam Rooms)
Why You Need to Move Fast: As one of Manhattan’s premier dedicated medical buildings, full floors and proposed prebuilt suites off Lexington Avenue are moving fast. Health systems needing contiguous space must secure their floor plates now.

9. 3 East 75th Street, Suite LL

Upper East Side • New York City

Size: 4,334 SF | Rate: $23,500 / month
Layout: 4 Offices | Open Administrative Space
Why You Need to Move Fast: Less than half a block from Central Park and Fifth Avenue, this massive 4,334 SF space features a dedicated entrance and an incredibly rare ground-level accessible lift.

10. 7 Lexington Avenue, Suite 3P

Gramercy / Midtown East • New York City

Size: 700 SF | Rate: $3,500 / month
Layout: 3 Exam Rooms
Why You Need to Move Fast: At just $3,500 a month for three distinct exam rooms, this is one of the most accessible rents in Manhattan. Solo practitioners and wellness specialists will face immediate competition for this footprint.

To learn more about leasing and purchase opportunities or to schedule an on-site tour, please contact our team directly.

About Wexler Healthcare & Commercial Properties

Wexler Healthcare & Commercial Properties is New York City’s premier healthcare real estate group. For over 40 years, the group has specialized in the leasing and sale of medical and healthcare properties across NYC, representing top-tier landlords and healthcare institutions.

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